BlackBerry Desktop Manager has been updated to V. 220.127.116.11.
Synchronization improvements for Media files and organizer data.
Support for 64-bit versions of Microsoft Outlook 2010 and Exchange 2010.
I could not find any Documents or official changelog for the updated version so if you notice anything different plaease leave a comment and let folks know.
The easiest way to get the update is to just open your desktop manager software and it will prompt to update automatically. If that is giving you problems you can upgrade here. http://us.blackberry.com/apps-software/desktop/